Easy Southern Chicken Spaghetti Recipe with RoTel - Restless Chipotle (2024)

This classic southern casserole has been a favorite for decades - mostly because it's easy to make and full of cheesy goodness!

Next time try this other easy family favorite, King Ranch Chicken Casserole! Serve either of these weeknight dinner casseroles with a batch of homemade garlic breadsticks!

🗝️ Key takeaways

• Takes just 30 minutes but you can also assemble ahead of time.
• We love this for busy weeknights and back to school.
• Leftovers are easy to warm up and it freezes like a charm - be sure to read through the freezing instructions in the storage section.

Gooey cheesy pasta, with tender chicken and plenty of Ro-Tel tomatoes with chiles for flavor- it's a great recipe the whole family will love.

Hearty cowboy spaghetti is another one of our favorites!

This simple casserole recipe uses cream of chicken soup and a frozen onion and green peppers mix to save time. The diced tomatoes and chiles give it a spicy kick!

My cheesy chicken spaghetti is one of the family's favorite recipes - I hope you love it as much as we do!

🧾 Ingredients

📖 Variations

Chicken spaghetti with RoTel in it is my favorite but this is a versatile dish with lots of potential variations!

• Switch to penne, macaroni, or your favorite pasta and have a delicious spicy chicken pasta bake!
• Turkey, ham, and cooked ground beef are ALL good in this versatile dinner recipe. In fact, it's a great way to use up leftover turkey after Thanksgiving!
• Stir in pimento.
• Saute some bell peppers with the onions.
• Next time try topping with breadcrumbs, crushed tortilla chips, or potato chips for a little added texture and crunch.
• If you like it spicy hot use the hot Rotel version instead of the mild Rotel.
• Boneless chicken thighs work as well as boneless chicken breasts if you prefer them.
• If you don't have cream of chicken soup you can use cream of mushroom soup, cream of celery soup, or cream of asparagus soup - they all work well. Or, make a homemade white sauce.
• You can use fresh onions and peppers instead of frozen ones - just use about ½ cup each and dice them. Be sure to saute before adding to the casserole dish.

Next time try this 15 minute cream cheese pasta recipe!

🔪 Instructions

Try it once and my easy chicken spaghetti recipe will be on your dinner rotation a lot!

1. Break the uncooked spaghetti noodles into 2 inch pieces.
2. Bring salted water to a boil in a large pot and cook the pasta.
3. Meanwhile mix the cream of chicken, the RoTel, and cream cheese in a microwave-safe large bowl. Microwave, stirring often, until it's all melted together.
4. Stir in the cheese to make a smooth sauce.
5. Shred the cooked chicken and set aside.
6. Add enough cream to the sauce to make it spoonable but not too thin.
7. Stir in the chicken.
8. Pour over the cooked spaghetti and stir well.
9. Spoon into an oiled casserole dish and top with Cheddar cheese. Bake.

🎥 Video

Lynn says: "I've been making Chicken Spaghetti for years but this really took it up a notch. Will be using this recipe from now on!"

Casserole times and temps

Need to bake your chicken spaghetti casserole at a different temperature than called for in the recipe? No problem!

These times are only an estimate. Be sure to check your casserole often. It's done when an instant-read thermometer registers 165F when stuck in the middle of the casserole.

🥫 Storage

You can assemble chicken spaghetti up to 2 days ahead of time, cover it with plastic wrap, refrigerate it, and then slip into the oven when you're ready to eat it. (Take the plastic wrap off before baking.)

Store leftovers in an airtight container or covered with plastic wrap in the refrigerator.

To reheat just pop into a 350F oven for about 15 -20 minutes, or microwave until warmed through.

How to freeze

Chicken spaghetti freezes like a charm baked or unbaked!!

Cool to room temperature. Cover it with plastic wrap then aluminum foil or put it in a freezer container and freeze for up to 3 months.

To bake:

Thaw overnight in the refrigerator then bake as directed. See the chart above for baking from frozen.

To warm up leftovers:

Thaw overnight in the refrigerator then heat in the microwave or bake in the oven for 15-20 minutes.

💭 Things to know

Expert Tip: Cook your chicken by simmering it in chicken stock to cover. When it's cooked through (165F) remove it and bring the stock back to a boil. Add the spaghetti to the chicken stock with enough water to cover. This gives your casserole even more flavor!

Restless Chipotle chicken spaghetti casserole is a little different from the bland recipes you often see.

The tomatoes and chiles add a sharp, mildly spicy flavor that cuts the richness of the cheese and creamy sauce and balances it out nicely.

• You can assemble this up to 3 days ahead of time and keep it covered in the fridge until you're ready to bake it.
• Chicken spaghetti with Rotel is freezer-friendly. It freezes well for up to 3 months.
• Put plastic wrap, parchment paper, or waxed paper over the top before sealing with aluminum foil or the acids from the tomatoes will react with the aluminum and it will taste awful.
• I've made this low carb and keto by using zucchini noodles instead of pasta. Still yummy!
• This is a great way to use leftover chicken!
• Break the spaghetti up in 2 to 3 inch pieces before cooking - it's traditional!
• For best results cook pasta just past done - don't stop at al dente. It will cook more (and soak up more flavor) as it bakes.
• You can use sour cream instead of cream cheese for a lighter, yet still creamy, sauce.
• Some people like to use half or all Velveeta cheese in the sauce instead of the shredded Cheddar.
• Shred the cheese from a block - don't buy pre-shredded. It is dusted with cellulose and doesn't melt as creamy as block cheese.
• Save time by using leftover chicken or rotisserie chicken from the store. You've gotta love planned leftovers - it's almost like a free meal!
• You can skip the baking and just mix it all up in a skillet if you like.
• Use one of the Rotel tomatoes variations like fire roasted or extra hot and spicy!
• Try this cream cheese chicken spaghetti if you want a super rich and creamy casserole - but it's going to cost you extra time on the treadmill.

👩🏻‍🍳 FAQs

Here are the questions I am most frequently asked about this creamy chicken recipe.

What’s new? Check out myRestless Chipotle & Co. Store on Amazon where you'll find all kinds of nostalgic goodness!Thanks so much for being a part of Restless Chipotle!

This angel chicken mac and cheese or Chicken Frito Pie casserole are also great recipes for bringing to someone or to take to a potluck.

• Taco Spaghetti is creamy good and all done in one pot.
• Copycat Panera Chicken Tortellini Alfredo is another one pot meal.
• Million Dollar Spaghetti is something like lasagna only so much easier!
• Chicken Bacon Ranch Pasta Bake is just so deliciously family friendly!
• Crack Chicken Spaghetti is an over the top version of this old favorite!
• This Tuna Casserole recipe has a crunchy, salty potato chip topping.

Here are more great chicken recipes.

🍽️ Serve with...

Keep it easy by choosing a few of these great side dishes for chicken spaghetti and some classic southern fried pies for dessert.

Dinner plans solved!

📞 The last word

Mmmm.... this easy chicken spaghetti recipe is my go to when I need comfort food! Next time try this crock pot chicken spaghetti. It's even easier.

If you click on the number of servings in the recipe card you can adjust the measurements up or down for the exact number of servings you need.

If you love this recipe please give it a 5 star rating.⭐️⭐️⭐️⭐️⭐️

📖 Recipe

✍🏻 A note from Marye...

I know y'all don't always like the stories bloggers tell so when I have one I try to put it at the very bottom so you can read or skip as you like.

🍲 Southern casserole culture

Homemade chicken spaghetti casserole is one of my favorites. It's creamy, rich, gooey, and cheesy - everything the ultimate comfort food should be.

This wasn't one of those things that my mom made, though.

This is a recipe that came from one of my neighbors when my kids were growing up -- I guess she took pity on me and my nightly dinners for 10 people or more.

A large family requires lots of food!

She brought a foil covered pan of this comforting casserole to my door one afternoon when I was SO exhausted, SO ready to quit, and SO full of "woe is me" that I was ready to bust.

It changed my entire day.

It's that simple. One dish of comfort food, one knock at the door at the right time, and someone suddenly has the energy to go on with life. Someone feels cared about.

Isn't that what makes life worth living?

I think so!

First published August 4, 2020. Last updated September 17, 2023, for editorial improvements and the temperature chart.

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