Ketosis: Definition, Benefits & Side Effects (2024)

What is ketosis?

Ketosis is a process that occurs when your body uses fat as its main fuel source. Normally, your body uses blood sugar (glucose) as its key energy source.

You typically get glucose in your diet by eating carbohydrates (carbs) such as starches and sugars. Your body breaks the carbohydrates down into glucose and then uses the glucose as fuel. Your liver stores the rest and releases it as needed.

When your carb intake is very low, these glucose stores drain down. Since your body doesn’t have enough carbs to burn for energy, it burns fat instead. As your body breaks down fat, it produces a compound called ketones. The ketones, or ketone bodies, become your body and brain’s main source of energy.

The fat your body uses to create ketones may come from your diet (nutritional ketosis), or it may come from your body’s fat stores. Your liver produces a small amount of ketones on its own. But when your glucose level decreases, your insulin level decreases. This causes your liver to ramp up the production of ketones to ensure it can provide enough energy for your brain. Therefore, your blood has high levels of ketones during ketosis.

Advertisem*nt

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

What is the ketosis diet?

The ketogenic (keto) diet changes the way your body uses food. Typically, carbohydrates in your diet provide most of the fuel your body needs. The keto diet reduces the number of carbs you eat and teaches your body to burn fat for fuel instead.

The keto diet is high in fat, moderate in protein and low in carbohydrates. The standard keto diet consists of 70% to 80% fats, 10% to 20% proteins and 5% to 10% carbohydrates.

Many nutrient-rich foods contain high amounts of carbohydrates. This includes whole grains, fruits and vegetables. Carbs from all sources are restricted on the keto diet. So you’ll have to cut out all bread, cereal and other grains and make serious cuts to your fruit and vegetable intake. The types of foods that provide fat for the keto diet include:

  • Meats and fish.
  • Eggs.
  • Nuts and seeds.
  • Butter and cream.
  • Cheese.
  • Oils such as olive oil and canola oil.

How many carbs do I need for ketosis?

You’ll need to stay under 50 grams of carbohydrates per day to enter and stay in ketosis. That’s about three slices of bread, two bananas or 1 cup of pasta.

Advertisem*nt

How long does it take to get into ketosis?

If you eat between 20 and 50 grams of carbohydrates each day, it will usually take you two to four days to enter ketosis. However, the time it takes to enter this state varies based on several factors. It may take you a week or longer to get into ketosis. Factors that may influence how long it takes you to achieve this state include your:

  • Age.
  • Carbohydrate, fat and protein intake.
  • Physical activity level.
  • Metabolism.
  • Sleep health.
  • Stress level.

If you eat a high-carb diet before starting a keto diet, it may take you longer to reach ketosis than someone who consumes a low-carb diet. That’s because your body needs to exhaust its glucose stores first.

You may be able to get into ketosis faster with intermittent fasting. The most common method of intermittent fasting involves eating all of your food within eight hours. Then, you fast for the remaining 16 hours of a 24-hour period.

What are the benefits of ketosis?

Research has shown that ketosis may have several health benefits. One of the biggest benefits of ketosis may be weight loss. The process can help you feel less hungry, which may lead to eating less food. It can help you lose belly fat (visceral fat) while maintaining a lean mass. Other possible benefits of ketosis include treating and managing diseases such as:

  • Epilepsy: Healthcare providers often put children with epilepsy on the keto diet to reduce or even prevent seizures by altering the “excitability” part of their brain.
  • Other neurologic conditions: Research has shown the keto diet may help improve neurological conditions such as Alzheimer’s disease, autism and brain cancers such as glioblastoma.
  • Type 2 diabetes: The keto diet can help people with Type 2 diabetes lose weight and manage their blood sugar levels.
  • Heart disease: The keto diet may lower your risk of developing cardiovascular disease by lowering your blood pressure, improving your HDL (“good”) cholesterol levels and lowering your triglycerides.
  • Metabolic syndrome: The keto diet may reduce your risk of developing metabolic syndrome, which is associated with your risk of heart disease.

Ketosis has also been shown to increase your focus and energy. The keto diet delivers your body’s energy needs in a way that reduces inflammation. Research suggests your brain works more efficiently on ketones than on glucose.

Advertisem*nt

What are the side effects of ketosis?

The keto diet has many benefits, but it may come with some side effects. One of the signs of ketosis may include “keto flu,” which includes symptoms such as upset stomach, headache and fatigue. Other symptoms of ketosis may include:

  • Bad breath (“keto” breath).
  • Constipation.
  • Insomnia.
  • Dehydration.
  • Low bone density (osteopenia) and bone fractures.
  • High cholesterol (hyperlipidemia).
  • Kidney stones.
Ketosis: Definition, Benefits & Side Effects (2024)

FAQs

Ketosis: Definition, Benefits & Side Effects? ›

Ketosis is a metabolic state that occurs when your body burns fat for energy instead of glucose. The keto diet has many possible benefits including potential weight loss, increased energy and treating chronic illness. However, the diet can produce side effects including “keto” breath and constipation.

What are the side effects of ketosis? ›

Common short-term side effects resulting from the initiation of KD have been referred to as “keto flu,” which encompasses symptoms including fatigue, headache, dizziness, nausea, vomiting, constipation, and low exercise tolerance [6].

Is ketosis good or bad for the body? ›

Ketone bodies can be used as fuel for the body. Ketosis has numerous health benefits and is safe for most people, but it may have some negative effects especially in the beginning, although these effects are typically not serious.

What are the pros and cons of ketosis? ›

Possible benefits of ketosis include weight loss, improved blood sugar management, and reduced seizures in children with epilepsy. However, following a strict ketogenic diet to induce ketosis can be difficult and lead to unwanted short-term side effects like headaches, stomach upset, dehydration, and bad breath.

What organ does ketosis affect? ›

This shift involves increasing fatty acid oxidation and production of ketones in the liver as an alternate energy source for the brain as well as the skeletal muscles, heart, and kidney. Low levels of ketones are always present in the blood and increase under circ*mstances of low glucose availability.

How long is it safe to be in ketosis? ›

Gulotta recommends staying on keto for six months max before reintroducing more carbs to your diet. And Scott Keatley, RDN, of Keatley Medical Nutrition Therapy in New York City, agrees: “The science hasn't gotten to the point where I would be comfortable recommending it as a forever diet,” he says.

Who should not do keto? ›

TABLE 2
Main contraindicationsMain arguments in support of contraindications
Recent stroke or myocardial infarctionIncreased risk of arrhythmia
Heart failureIncreased risk of arrhythmia, hydroelectrolitic alterations
Respiratory failureAcidosis
Active/severe infectionsImmunosuppression
11 more rows
Jul 10, 2020

Is it OK to be in ketosis all the time? ›

But for weight loss and general well-being in healthy adults, there's no need to be in ketosis all the time. People who typically do keto might benefit from short periods out of ketosis, and people who aren't fully on the keto train might benefit from switching to a fat-burning metabolism every now and again.

Why do I feel better in ketosis? ›

Anecdotal evidence links the initial phase of fasting or a low-carbohydrate diet with feelings of well-being and mild euphoria. These feelings have often been attributed to ketosis, the production of ketone bodies which can replace glucose as an energy source for the brain.

Is ketosis hard on kidneys? ›

The ketogenic diet is becoming more popular as a weight loss regimen; however, the evidence has failed to show clinically significant benefits over comparator diets. Even worse, it may cause hyperlipidemia, vitamin and mineral deficiencies, fatigue, and kidney damage, among other complications (Figure 1) [6].

Is ketosis hard on your liver? ›

A high-fat diet like the keto diet can cause fat to build up in your liver and lead to fatty liver disease. Animal studies suggest the keto diet can cause non-alcoholic fatty liver disease, or NAFLD, and raise liver enzyme levels.

What organs is keto hard on? ›

The keto diet could cause low blood pressure, kidney stones, constipation, nutrient deficiencies and an increased risk of heart disease. Strict diets like keto could also cause social isolation or disordered eating. Keto is not safe for those with any conditions involving their pancreas, liver, thyroid or gallbladder.

How will I feel when my body goes into ketosis? ›

One of the signs of ketosis may include “keto flu,” which includes symptoms such as upset stomach, headache and fatigue. Other symptoms of ketosis may include: Bad breath (“keto” breath). Constipation.

Is it bad to be in ketosis all the time? ›

Ketosis is likely safe for most people, especially if they follow it with a doctor's supervision. However, it can have some negative effects, especially at the start. It's also unclear how a ketogenic diet may affect the body long term ( 7 ).

What happens when you take your body out of ketosis? ›

Weight gain. Bloating and other bathroom issues. Blood sugar spikes, which could cause fatigue and irritability. Increased hunger and sugar addiction.

What foods should you avoid on keto diet? ›

By staying away from grains, sugary foods, high-carb fruits, and starchy vegetables, you set yourself up for a smoother transition into ketosis. Additionally, steer clear of processed foods, alcohol, and condiments that may contain hidden carbs.

Top Articles
Latest Posts
Article information

Author: Pres. Lawanda Wiegand

Last Updated:

Views: 5961

Rating: 4 / 5 (71 voted)

Reviews: 94% of readers found this page helpful

Author information

Name: Pres. Lawanda Wiegand

Birthday: 1993-01-10

Address: Suite 391 6963 Ullrich Shore, Bellefort, WI 01350-7893

Phone: +6806610432415

Job: Dynamic Manufacturing Assistant

Hobby: amateur radio, Taekwondo, Wood carving, Parkour, Skateboarding, Running, Rafting

Introduction: My name is Pres. Lawanda Wiegand, I am a inquisitive, helpful, glamorous, cheerful, open, clever, innocent person who loves writing and wants to share my knowledge and understanding with you.